JB Lubin
Assistant Professor of Microbiology and Immunology
Microbial Genetics and Biochemistry, Mucosal Immunology, Early-Life Host-Microbiota Interactions
Molecular Biology Program
Education
B.S. State University of New York
Ph.D. University of Delaware
Research
Our lab is dedicated to understanding how the metabolic function of the early-life microbiome impacts infant health. Our work focuses on the interplay between host nutrition and microbial metabolism in relation to neonatal infections and immunity and how host-microbiota interactions from birth to weaning influence atopy.
References
Selected Publications
- Lubin, J.B., Green, J., Maddux, S., Denu, L., Duranova, T., Lanza, M., Wynosky-Dolfi, M., Flores, J.N., Grimes, L.P., Brodsky, I.E., Planet, P.J., and M.A. Silverman. 2023. Arresting microbiome development limits immune system maturation and resistance to infection in mice. Cell Host and Microbe. 31(4):554-570.e7
- Conrey, P.E., Denu, L., O’boyle, K.C., Rozich, I., Green, J., Maslanka, J., Lubin, J.B., Duranova, T., Haltzman, B.L., Gianchetti, L., Oldridge, D., De Luna, N., Vella, L.A., Allman, D., Spergel, J., Tanes, C., Bittinger, K., Henrickson, S.E., and M.A. Silverman. 2023. IgA deficiency destabilizes homeostasis towards intestinal microbes and increases systemic immune dysregulation. Science Immunology. 8(83): eade2335.
- Lubin, J.B., Silverman, M.A., and P.J. Planet. 2024. Comparison of gnotobiotic communities reveals milk-adapted metabolic functions and unexpected amino acid metabolism by the pre-weaning microbiome. Gut Microbes. 16(1).
- Lubin, J.B., Planet, P.J., and M.A. Silverman. 2025. Microbial succession at weaning is guided by microbial metabolism of host glycans. Microbiome. Accepted.