We are a multi-disciplinary group seeking to illuminate drug and disease mechanisms and pharmaceutical delivery through the use of advanced imaging techniques, molecular therapeutics, and combining the two into theranostics. Our current research spans three different but inter-related directions:

1. We utilize cutting-edge imaging technologies including positron emission tomography and optoacoustic imaging to quantitatively and noninvasively visualize disease microenvironment to develop predictive and response biomarkers.
2. We apply biochemical strategies to modulate proteins, antibodies and peptides to develop next-generation drug conjugates, with a particular focus on radionuclide therapies.
3. We apply imaging to determine pharmacokinetics and pharmacodynamics and target engagement of novel therapies to enable evidence-guided rational design and translation of advanced therapies.

Students joining the lab will work in an integrated, collaborative environment with the opportunity to contribute to several high risk- high reward projects at the interface of molecular imaging and therapy. Our lab provides highly interdisciplinary training spanning molecular biology, biochemistry, molecular therapy, radiochemistry and imaging sciences that allow us to make unique, high-impact contributions to cancer therapy.

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